An Improved End-to-End Micro-expression Recognition System for Real-world Videos via Dual-input CNN Architecture
Expert Systems with Applications · IF 8.5 Q1
智慧醫療與代謝生理實驗室Smart Healthcare & Metabolic Physiology Lab
Min-Huan Wu, Ph.D.吳旻寰 博士
東海大學 高齡健康與運動科學研究所 教授兼所長
高齡健康與運動科學學士學位學程 主任
Professor & Director, Graduate Institute of Senior Health and Exercise Science
Chair, BSc Programme in Senior Wellness and Sports Science
Tunghai University, Taichung, Taiwan
研究高齡者的代謝與肌肉功能衰退,涵蓋分子機轉、運動處方與量測技術。 Research on metabolic and muscular decline in ageing — mechanism, exercise prescription, measurement.
總覽Overview
台灣已進入超高齡社會,多重慢性病是主要的照護負擔,而能夠開立與監測運動、營養處方的專業人力不足。實驗室的研究圍繞這個問題展開,涵蓋分子層次的致病機轉、臨床運動處方,以及相關的量測與資訊技術。 Taiwan has become a super-aged society. Multimorbidity is the dominant care burden, and there are too few professionals able to prescribe and monitor exercise and nutrition. The lab's research addresses this across three areas: molecular mechanisms of disease, clinical exercise prescription, and the related measurement and computing technology.
近五年於 SCIE 期刊發表逾 20 篇論文,多篇屬 Q1/Q2 等級。部分研究成果以裝置或系統的形式與廠商合作開發,包括取得醫療器材專利、輔導團隊入選 TTA 台灣百大新創,以及整合七家廠商建置智慧化健身房方案。另擔任經濟部、衛福部、教育部與地方政府多項計畫的審查委員。 Over the past five years, more than 20 papers in SCIE journals, several in Q1/Q2 venues. Some results have been developed with industry partners into devices or systems, including medical-device patents, mentored teams selected for the TTA Taiwan Top 100 startups, and a smart-gym package integrating seven companies. Also serves as a review committee member for the Ministry of Economic Affairs, Ministry of Health and Welfare, Ministry of Education and local governments.
研究Research
研究領域涵蓋高齡醫學、運動醫學與醫療科技三部分,分別處理高齡者功能衰退的不同層面:分子層次的致病機轉、臨床層次的運動處方,以及評估與量測所需的技術。以下依時間順序說明研究重心的轉變。 The research covers geriatric medicine, exercise medicine and health technology, addressing different levels of functional decline in ageing: disease mechanisms at the molecular level, exercise prescription at the clinical level, and the technology required for assessment and measurement. The three periods below are listed chronologically.
博士訓練於中國醫藥大學基礎醫學研究所。研究以內皮素(ET-1)、microRNA、Visfatin、IGFBP-3 等訊息傳導路徑為主,探討發炎反應與代謝失衡如何影響軟骨、骨骼肌與血管的病理變化。 Doctoral training in basic medical science at China Medical University. The work focused on ET-1, microRNA, visfatin and IGFBP-3 signalling pathways, examining how inflammation and metabolic imbalance affect cartilage, skeletal muscle and vasculature.
ET-1|microRNA|Visfatin|IL-6 / TNF-α|腫瘤轉移|軟骨與骨骼肌發炎ET-1|microRNA|Visfatin|IL-6 / TNF-α|tumour metastasis|cartilage and muscle inflammation
研究重心轉向臨床應用,包括心肺運動科學、肌少症與共病症、冠心病與透析患者的運動治療,以及營養增補策略。合作場域以醫院與社區據點為主,重點在於運動劑量的設定與監測。 The focus moved to clinical application: cardiopulmonary exercise science, sarcopenia and multimorbidity, exercise therapy for coronary and dialysis patients, and nutritional supplementation. The settings were mainly hospitals and community sites, with an emphasis on setting and monitoring exercise dose.
肌少症|心肺復健|共病症|運動處方|營養增補sarcopenia|cardiopulmonary rehabilitation|multimorbidity|exercise prescription|nutrition
臨床評估受限於專業人力與量測工具,研究因此延伸至影像與感測技術,包括骨架偵測、深度學習骨質疏鬆篩檢、微表情辨識、呼吸代謝感測,以及 AIoT 遠距照護系統的開發與驗證。 Clinical assessment is constrained by the availability of specialists and measurement tools. The work therefore extended into imaging and sensing: pose estimation, deep-learning osteoporosis screening, micro-expression recognition, respiratory-metabolic sensing, and the development and validation of AIoT telecare systems.
深度學習|骨架偵測|醫療影像判讀|穿戴感測|AIoT|遠距照護deep learning|pose estimation|medical imaging|wearable sensing|AIoT|telecare
以下為登錄的三個研究領域。The three registered research domains.
糖尿病、肥胖型肌少症、癌症醫學,以及中草藥與益生菌的機能性驗證。Diabetes, sarcopenic obesity, cancer medicine, and functional validation of herbal and probiotic interventions.
心肺運動科學、臨床運動治療與營養增補策略,為高風險族群建立可執行、可監測的處方。Cardiopulmonary exercise science, clinical exercise therapy and nutritional strategies — executable, monitorable prescriptions for high-risk populations.
物聯網裝置、APP 開發、影像識別與神經網路分析,用於降低評估工作對專業判讀人力的依賴。IoT devices, app development, image recognition and neural network analysis, used to reduce the reliance of assessment on specialist readers.
著作與計畫Publications & grants
完整清單與引用統計請見 Google Scholar。以下為近年具代表性的 Q1/Q2 期刊論文。Full record and citation counts on Google Scholar. Selected recent Q1/Q2 papers below.
An Improved End-to-End Micro-expression Recognition System for Real-world Videos via Dual-input CNN Architecture
Expert Systems with Applications · IF 8.5 Q1
Enhanced osteoporosis screening via multi-output deep learning: segmentation and classification of metacarpal radiographs
European Journal of Radiology, 194:112507 · IF 3.3 Q2
Endothelin-1-mediated miR-let-7g-5p triggers interleukin-6 and TNF-α to cause myopathy and chronic adipose inflammation in elderly patients
Aging (Albany NY) · IF 5.0 Q1
IGFBP-3 stimulates human osteosarcoma cell migration by upregulating VCAM-1 expression
Life Sciences · IF 5.1 Q1
Visfatin increases VEGF-dependent angiogenesis of endothelial progenitor cells during osteoarthritis progression
Cells · IF 5.2 Q1
Visfatin promotes IL-6 and TNF-α production in human synovial fibroblasts by repressing miR-199a-5p through ERK, p38 and JNK signaling pathways
獲東海大學高引用期刊論文獎(110 年度)Tunghai University Highly-Cited Paper Award, 2021
歷年國科會補助紀錄可於 國科會研究人才查詢系統 檢視完整內容。Complete funding record via the NSTC researcher database.
2026 年第 21 屆全國體育運動學術團體聯合年會暨國際學術研討會21st Joint Annual Conference of National Physical Education and Sport Societies, 2026
國科會 國內舉辦國際學術研討會 · 計畫主持人NSTC international conference grant · PI
台日合作間歇走路運動指導之實作學習成效研究Taiwan–Japan collaboration: learning outcomes of interval walking training instruction
教育部 教學實踐研究計畫(2025–2026) · 計畫主持人MOE teaching practice research, 2025–2026 · PI
結合智慧物聯網之老人運動數位照護師——以營養分析與疲勞度監控為例An AIoT digital care assistant for senior exercise: nutrition analysis and fatigue monitoring
教育部計畫(2025–2026) · 計畫主持人MOE project, 2025–2026 · PI
應用深度學習動作辨識結合歐盟長者活力體能訓練方案之 AI 健康分級檢測技術研究AI health-grading assessment combining deep-learning action recognition with the EU Vivifrail programme
國科會 產學合作研究計畫(2024–2025) · 服務系統與科技管理 · 計畫主持人NSTC industry–academia project, 2024–2025 · PI
牛樟芝純化物在軟骨細胞分化及降解的機制探討及對於關節炎的治療作用Antrodia cinnamomea compounds in chondrocyte differentiation, degradation and arthritis treatment
國科會 專題研究計畫 · 中醫藥學 · 計畫主持人NSTC general research project, Chinese medicine · PI
智慧化環狀等速肌力訓練暨特殊族群運動處方解決方案Smart isokinetic circuit training and exercise prescriptions for special populations
國科會 產學合作研究計畫 · 運動生理學 · 計畫主持人NSTC industry–academia project, exercise physiology · PI
創新超聲波呼吸器建構高齡慢性呼吸肺阻塞 AI 診斷服務系統An innovative ultrasonic respirator for an AI diagnostic service system in geriatric COPD
國科會 產學合作研究計畫(應用型) · 計畫主持人NSTC applied industry–academia project · PI
短期密集運動治療對冠狀動脈疾病患者之紅血球釋放一氧化氮機制與其流變學功能之影響Short-term intensive exercise therapy on erythrocyte nitric oxide release and haemorheology in coronary artery disease
國科會 專題研究計畫 · 復健 · 共同主持人NSTC rehabilitation project · Co-PI
AIoT 技術在智慧羽球系統應用及驗證Application and validation of AIoT in a smart badminton system
國科會 產學合作研究計畫(應用型) · 物聯網技術開發 · 共同主持人NSTC applied IoT project · Co-PI
建構結合正規及非正規之失智照顧服務系統——以社區型失智日間照顧中心為例A dementia care service system combining formal and informal care: community day-care centres
國科會 專題研究計畫 · 共同主持人NSTC research project · Co-PI
落實 USR 計畫建構優質高齡支持系統——東海大學青銀智慧行動車之健康促進研究與服務實踐USR programme: health promotion research and service practice of the Tunghai intergenerational smart mobile unit
教育部 大學社會責任計畫(2018–2021) · 共同主持人MOE University Social Responsibility programme, 2018–2021 · Co-PI
臺灣高齡社會的關鍵議題與挑戰——優質人性化生活科技與老人健康照護需求之研究Key issues in Taiwan's ageing society: humanised living technology and elderly healthcare needs
國科會 整合型計畫子計畫三 · 共同主持人NSTC integrated programme, sub-project 3 · Co-PI
產學落地Translation
以下為十件與廠商合作開發的技術與產品,各有合作廠商、實體成品與驗證場域。點圖可放大。 Ten technologies and products developed with industry partners. Each has a named partner, a physical output and a validation setting. Click any image to enlarge.
2022
以影像辨識與骨架偵測判讀啞鈴與手部動作,結合遊戲化設計用於居家運動復健,並記錄運動量。Image recognition and pose estimation read the dumbbell and hand movement. Combined with a gamified design, the system supports home-based rehabilitation and records exercise volume.
2022
以雷射測速儀換算油壓阻力設備在運動過程中的功率與速度,用以量化運動量並推導運動處方。A laser velocity sensor computes power and speed on hydraulic resistance equipment during movement, quantifying exercise volume and deriving a prescription from it.
2021
可攜式的呼吸代謝偵測裝置,即時顯示代謝量並提供每日飲食攝取建議。A portable respiratory metabolic analyser giving a real-time metabolic readout and daily dietary recommendations.
2020
以超聲波技術量測肺功能,應用於慢性阻塞性肺病與 COVID-19 的肺功能監控;並以此技術延伸建構高齡慢性呼吸 AI 診斷服務系統。Ultrasonic pulmonary function measurement for COPD and COVID-19 monitoring, extended into an AI diagnostic service system for chronic respiratory disease in older adults.
2019 — 2020
結合物聯網感測與場地數據,用於連續記錄運動表現與訓練負荷並提供回饋。IoT sensing combined with venue data, used to record performance and training load continuously and provide feedback.
2020
以心率量化演算法,讓指導者同時監看多位參與者的即時運動強度,用於團體課程的強度控制。A heart-rate quantification algorithm allows an instructor to monitor several participants' real-time intensity simultaneously, for intensity control in group sessions.
2018 — 2021
結合物聯網生理檢測、現場運動處方開立與醫院後送支援的行動服務車,在社區據點提供檢測、處方與課程。A mobile unit combining IoT physiological testing, on-site exercise prescription and hospital referral support, delivering testing, prescription and programmes at community sites.
2019
以八字迴旋的電動椅結合視覺回饋進行前庭覺訓練,找出旋轉速度、前庭覺變化與平衡、柔軟度之間的關聯。A figure-of-eight rotating powered chair with visual feedback, identifying the relationship between rotation speed, vestibular change, balance and flexibility.
2019
比較水波式冷/熱敷按摩眼罩對生理數值的影響,從反應力、柔軟度、平衡能力等指標的變化,反推合適的介入時間。Comparing the physiological effect of wave-type cold and hot compress eye masks — reaction, flexibility and balance measures used to derive an appropriate intervention duration.
2018 — 迄今present
與虹映科技合作發展高齡族群的運動處方指標,後續延伸至與醫療體系合作,將個人化運動量應用於疾病的運動治療。Developed with Hongying Technology as an exercise prescription index for older adults, later extended through hospital collaboration to apply individualised exercise dosing in disease treatment.
「手持式呼吸檢測儀」,與傑尼斯生醫共同開發,為高齡慢性呼吸 AI 診斷服務系統的量測元件。相關的超聲波呼吸測定技術另獲發明專利。A handheld respiration analyzer co-developed with Genesis Biomedical, serving as the sensing component of the AI diagnostic service system for chronic respiratory disease. The related ultrasonic respiration measurement technology holds a separate invention patent.
2023 年整合上岳科技、智順科技、拉斯維爾等七家公司,建置智慧化健身房方案,目的在降低高齡健身設備的導入成本。In 2023, seven companies including Shang-Yueh, Chih-Shun and Las-Well were integrated into a smart-gym package, intended to lower the deployment cost of senior fitness equipment.
榮譽Honors
以下為歷年獲得的獎項,領域涵蓋基礎藥理、醫學資訊與資訊系統。Awards received to date, spanning pharmacology, medical informatics and information systems.
與信州大學合作,將「間歇走路運動訓練」(IWT)系統導入台灣,並實際應用於嘉義長庚醫院與社區據點,成為教育部教學實踐研究計畫的主題。Working with Shinshu University to bring the interval walking training (IWT) system to Taiwan, deployed at Chiayi Chang Gung Memorial Hospital and community sites, and taken up as an MOE teaching practice research project.
與南澳洲大學運動科學系建立雙邊合作計畫,推動師生交流與共同研究。A bilateral collaboration with the exercise science department at the University of South Australia, supporting staff and student exchange and joint research.
受邀擔任 ACSM 美國運動醫學會年度全球產業趨勢評論作家的台灣代表;並於 PACIS 擔任副編輯、獲最佳副編輯獎。Invited as Taiwan's representative commentator for the ACSM annual global fitness trends survey; served as associate editor at PACIS, receiving the Best Associate Editor Award.
獎狀、專利證明與受獎紀錄。點縮圖可放大檢視。Certificates, patent records and award correspondence. Click a thumbnail to enlarge.
科普與媒體Outreach
以專書、專欄、廣播與電視節目等形式,向一般讀者與產業界說明高齡健康、預防醫學與健康科技的相關內容。Books, columns, radio and television programmes explaining ageing health, preventive medicine and health technology to general readers and to industry.
點縮圖放大,或直接點下方清單前往原始連結。Click a thumbnail to enlarge, or use the list below to open the original source.
以下連結皆已確認可正常開啟。All links below have been checked and resolve correctly.
AnkeCare口腔照護・AIOral care · AI
【吳旻寰專欄】借鏡國際健康獎勵機制 健康幣整合三階段:改變健康軌跡↗
AnkeCare長照 3.0・健康幣政策Long-term care 3.0 · health incentives
ACSM Top Fitness Trends 2026 — 台灣區運動產業趨勢評論專家Taiwan commentator↗
ACSM美國運動醫學會全球產業趨勢評論,受邀擔任台灣代表評論作家Invited Taiwan representative for the ACSM annual global trends survey
中天新聞台CTi News小麥的健康筆記・受邀學者Wheat's Health Notes · invited academic
AnkeCare預防醫學・基因檢測Preventive medicine · genetic testing
AnkeCare大數據・AI・高齡科技Big data · AI · gerontechnology
AnkeCare運動處方・AI 輔助Exercise prescription · AI assistance
AnkeCare預防醫學・共病症Preventive medicine · multimorbidity
好好聽 FMHaoHaoTing FM廣播節目主持人Radio programme host
好好文創HaoHao Culture全台 10 場次・講者10 events nationwide · speaker
客家新聞台Hakka TV村民大會・受邀學者Village Assembly · invited academic
EP41 擇你所愛,愛你所擇 — 學術歷程專訪interview on an academic path↗
Podcast東海大學高齡健康與運動科學學位學程專訪Long-form interview
公共服務Public service
包含中央部會與地方政府的計畫審查、產業界的技術顧問,以及學協會的組織工作。Proposal review for central and local government, technical advisory work for industry, and roles in professional associations.
人才培育Mentoring
擔任高齡健康與運動科學研究所所長及學程主任期間,以課程規劃與學生實務能力的培養為主要工作,並指導學生參與競賽、擔任校隊與社團的指導老師。As institute director and programme chair, the main work is curriculum planning and building students' practical capability, alongside supervising competition entries and coaching university teams and clubs.
指導學生開發「間歇走路運動訓練 APP」與「電子手套遠距復健系統」,獲東海大學跨系創新創業競賽佳作及評審團創新獎;並輔導學生參加全國中軟約農盃智慧醫療組獲第三名。Supervised student development of an interval walking training app and an electronic-glove tele-rehabilitation system, earning a merit award and the jury innovation prize at the Tunghai cross-departmental entrepreneurship competition; also mentored the team placing third in the smart healthcare track of the national IEC competition.
開設運動營養學、運動處方、營養學、智慧健康照護實務、病理學、運動生理學與實驗等課程,並將產學合作案例納入課程內容。Courses taught include sports nutrition, exercise prescription, nutrition, smart health care practice, pathology, and exercise physiology, with industry collaboration cases incorporated into the course material.
擔任東海大學田徑隊教練、跆拳道社與飛盤社輔導老師期間的指導成績。Results achieved while serving as Tunghai athletics coach and advisor to the taekwondo and ultimate frisbee clubs.
| 年度Year | 競賽名稱Competition | 等級/類型Level / event | 名次Place | 獲獎運動員Athlete | 身分Role |
|---|---|---|---|---|---|
| 2020 | 2020 中區盃飛盤爭奪賽2020 Central Taiwan Ultimate Frisbee Cup | 地區賽Regional | 1 | 東海大學飛盤社Tunghai Ultimate Frisbee Club | 社團輔導老師Club advisor |
| 2020 | CMLU TO ChinYi 飛盤邀請賽CMLU to ChinYi Frisbee Invitational | 地區賽Regional | 2 | 東海大學飛盤社Tunghai Ultimate Frisbee Club | 社團輔導老師Club advisor |
| 2019 | 大專盃田徑賽National Collegiate Athletics Championships | 全國・女子七項全能National · women's heptathlon | 2 | 謝佳蓉Hsieh Chia-jung | 田徑隊教練Athletics coach |
| 2018 | 大專盃田徑賽National Collegiate Athletics Championships | 全國・女子七項全能National · women's heptathlon | 3 | 謝佳蓉Hsieh Chia-jung | 田徑隊教練Athletics coach |
| 2017 | 全國大專院校運動會National Intercollegiate Athletic Games | 全國賽・女子七項混合運動National · women's heptathlon | 6 | 謝佳蓉Hsieh Chia-jung | 田徑隊教練Athletics coach |
| 2017 | 全國大專院校運動會National Intercollegiate Athletic Games | 全國賽・女子 100 公尺決賽National · women's 100 m final | 7 | 柯語茹Ko Yu-ju | 田徑隊教練Athletics coach |
| 2017 | 全國大專院校運動會National Intercollegiate Athletic Games | 全國賽・女子 200 公尺決賽National · women's 200 m final | 7 | 柯語茹Ko Yu-ju | 田徑隊教練Athletics coach |
| 2017 | 全國大專院校運動會National Intercollegiate Athletic Games | 全國賽・跆拳道黑帶二量級National · taekwondo, black belt | 6 | 徐芷Hsu Chih | 跆拳道社輔導老師Taekwondo club advisor |
學術足跡Elsewhere
以下為官方或機構維護的頁面。Pages maintained by official or institutional sources.
聯絡Contact
實驗室常態招收碩士生,也接受大學部專題生。研究題目多半同時涉及臨床場域與資料分析,不要求兩方面都已具備基礎。The lab takes master's students year-round and accepts undergraduate project students. Projects typically involve both a clinical setting and data analysis; a background in both is not required.
運動科學、物理治療、護理、健康管理背景,可在實驗室補足程式與資料分析能力。For those from exercise science, physiotherapy, nursing or health management — coding and data analysis skills can be developed here.
資工、電機、資料科學背景,可在實驗室接觸實際的臨床場域與研究資料。For those from computer science, electrical engineering or data science — access to real clinical settings and research data.
裝置驗證、臨床試驗設計、演算法開發,以及 SBIR 與產學合作計畫的共同提案。Device validation, trial design, algorithm development, and joint SBIR or industry–academia grant applications.
東海大學 農業暨健康學院 高齡健康與運動科學研究所
台中市西屯區台灣大道四段 1727 號 · (04) 2359-0121 轉 37501
Graduate Institute of Senior Health and Exercise Science, College of Agriculture and Health, Tunghai University
No. 1727, Sec. 4, Taiwan Blvd., Xitun District, Taichung, Taiwan · +886-4-2359-0121 ext. 37501